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apalutamide will minimize the extent or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with medicines which are CYP3A4 substrates may end up in lessen exposure to these remedies.As such, these possible future purposes should be re

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